Naloxone is an special narcotic drug which reverses the sequels of other narcotic medicines. Naloxone is a drug used to retaliate the effects of opioid overdose. Opioid is a chemical substance which has a morphine-like action in the body. The prime use is for pain relief. These agents work by pledging to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract. The receptors in these two organ systems mediate both the propitious effects, and the undesirable side effects are for example heroin or morphine overdose.
Naloxone may also be used to treat narcotic drug overdose or to diagnose narcotic drug addiction. Naloxone prevents or counters the effects of opioids including respiratory depression, sedation and hypotension. Also, it may reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine.
Naloxone hydrochloride does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the nonappearance of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity. Naloxone hydrochloride, a narcotic antagonist, is a synthetic congener of oxymorphone. In structure it varies from oxymorphone in that the methyl group on the nitrogen atom is replaced by an allyl group.
Naloxone is orchestrated from thebaine. Naloxone is injected, usually initially intravenously for indelible action. Naloxone is given as an injection under the skin, into a muscle, or into a vein. The drug also cloggs the action of pain-lowering endorphins which the body produces naturally. The patent for Naloxone has expired and the drug is presently available in various generic forms.
Naloxone has no other use in Suboxone other than preventing users from injecting the Suboxone in the body. Yet, the Naloxone in Suboxone does cause side effects in some people. These side effects constitute, but are not limited to, asthenia, chills, headache, infection, pain, pain in the abdomen, back pain, withdrawal syndrome, vasodilation, constipation, diarrhea, nausea, vomiting, insomnia, and sweating. Naloxone can cause side effects which may vitiate your thinking or reactions. Be coutious if you drive or do anything which requires you to be awake and alert. Avoid drinking alcohol while taking naloxone. Alcohol may increase dizziness caused by naloxone.
Itís fascinating that scientists learned how to treat drug addiction, or some types of it at least, by making use of other equally addictive drugs for the process.
Side effect of Naloxone