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Home :: Digestive Disorders

Gastric Erosion

 

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Gastric Erosion is a minor ulceration of the gastric mucosa. A localized inflammation or minor ulceration of the stomach lining. Gastric erosion is a  slight break (or "ulceration") in the innermost layer (called "mucosa") of the stomach's lining. If an ulceration extends deeper than this layer, it is called a gastric ulcer. Gastrosplenic fistula resulting from erosion of a primary splenic lymphoma is a rare cause of massive upper gastrointestinal hemorrhage associated with benign peptic ulcer disease, gastric Crohn's disease, gastric adenocarcinoma, and primary gastric and splenic lymphomas. It is concluded from these results that IL-1 acts mainly in the central nervous system to inhibit the occurrence of stress-induced gastric erosion and that the IL-1 beta-induced inhibition of gastric erosion is mediated by prostaglandin in a manner that is independent of brain CRF. See also duodenal ulcer , which is a break in the normal tissue lining the duodenum (the first part of the small bowel).

Causes of Gastric Erosion

The common Causes of Gastric Erosion :

  • Drugs like aspirin and steroid.
  • cortisone drugs (steroids) used to treat asthma,Addison's disease or other conditions;
  • Benign gastric ulcers are caused by an imbalance between the secretion of acid and an enzyme called pepsin and the defenses of the stomach mucosal lining.
  • This leads to inflammation and may be precipitated by aspirin and nonsteroidal anti-inflammatory medications (NSAIDs) such as ibruprofen.

Symptoms of Gastric Erosion

Some are common Gastric Erosion :

  • Stomach bleeding
  • Blood in stools or black, tarry stools
  • Anemia
  • Weight loss
  • Fatigue
  • Black stool
  • Nasea
  • Abdominal indigestion
  • Blood in stools or black, tarry stools

Treatment of Gastric Erosion

Here is the list of the methods for treating Gastric Erosion :

  • Multiple regimens are effective and usually include either an H2 receptor antagonist such as famotidine (Pepcid) or nizatidine (Axid) or a proton pump inhibitor such as omeprazole (Prilosec) or esomeprazole (Nexium) to suppress acid, combined with two antibiotics.
  • Surgical intervention may be recommended for people who do not respond to medical therapy or to endoscopic therapy for bleeding.
  • However, combined treatment with estrogen and lithium, significantly decreased the severity of gastric erosions in intact but not in ovariectomized rats and this was associated with a significant increase in the endogenous histamine content of the gastric mucosa.
  • Avoiding smoking
  • Avoiding tea, coffee , and soft drinks containing caffeine